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PDS5B Antibody - middle region : Biotin (ARP58313_P050-Biotin)

Product Specifications

Gene Name

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

Gene Aliases

AS3, APRIN, CG008

Gene ID

23047

Swiss Prot

Q9NTI5

Accession Number

NP_055847

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PDS5B

Target

PDS5B plays a role in androgen-induced proliferative arrest in prostate cells. It is required for maintenance of sister chromatid cohesion during mitosis. Defects in PDS5B may be the cause of some cancers including esophageal cancer.

Partner Proteins

UBC; EED; RNF2; CDCA5; LAMP2; APP; NSMCE2; SIRT7; RAD21; STAG2; STAG1; SMC3; SMC1A; SUMO1; WAPAL; WFDC5; PDS5A; tat

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PDS5B is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

159kDa

References & Citations

Gregory, S.G., (2006) Nature 441 (7091), 315-321

Shipping Conditions

Wet Ice

Protein Length

1447

NCBI Gene Symbol

PDS5B

NCBI GB Accession Number

PDS5B

Host or Source

Rabbit

Protein Name

Sister chromatid cohesion protein PDS5 homolog B

Nucleotide Accession Number

NM_015032

Peptide Sequence

DEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMK

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