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H2AFX Antibody - middle region : HRP (ARP58281_P050-HRP)

Product Specifications

Gene Name

H2A histone family, member X

Gene Aliases

H2A.X, H2A/X, H2AFX

Gene ID

3014

Swiss Prot

P16104

Accession Number

NP_002096

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human H2AFX

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA

Partner Proteins

UBC; HIST1H3A; USP17L2; UBD; RNF8; DDX21; XRCC6; NBN; NCL; HIST1H3B; ESR1; CENPA; TP53BP1; TOPORS; MDC1; BRCA1; ATR; ATM; PRKDC; CBX5; TRIM28; EGFR; BMI1; HIST2H3C; PML; XRCC5; UBB; TERF2; RNF2; SIRT7; CSNK2A1; ARRB2; ARRB1; PAXIP1; MRE11A; ATF2; MCPH1; C

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IF, IHC, WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that H2AFX is expressed in NCIH226

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 79%; Rat: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

16kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-H2AFX (ARP58281_P050-HRP) antibody

Protein Length

143

NCBI Gene Symbol

H2AFX

NCBI GB Accession Number

H2AFX

Host or Source

Rabbit

Protein Name

Histone H2A.x

Nucleotide Accession Number

NM_002105

Peptide Sequence

ELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQE

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