H2AFX Antibody - middle region : HRP (ARP58281_P050-HRP)
Product Specifications
Gene Name
H2A histone family, member X
Gene Aliases
H2A.X, H2A/X, H2AFX
Gene ID
3014
Swiss Prot
P16104
Accession Number
NP_002096
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human H2AFX
Target
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA
Partner Proteins
UBC; HIST1H3A; USP17L2; UBD; RNF8; DDX21; XRCC6; NBN; NCL; HIST1H3B; ESR1; CENPA; TP53BP1; TOPORS; MDC1; BRCA1; ATR; ATM; PRKDC; CBX5; TRIM28; EGFR; BMI1; HIST2H3C; PML; XRCC5; UBB; TERF2; RNF2; SIRT7; CSNK2A1; ARRB2; ARRB1; PAXIP1; MRE11A; ATF2; MCPH1; C
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IF, IHC, WB
Purification
Affinity Purified
Sample Type
There is BioGPS gene expression data showing that H2AFX is expressed in NCIH226
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 79%; Rat: 86%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
16kDa
Shipping Conditions
Wet Ice
Protein Length
143
NCBI Gene Symbol
H2AFX
NCBI GB Accession Number
H2AFX
Host or Source
Rabbit
Protein Name
Histone H2A.x
Nucleotide Accession Number
NM_002105
Peptide Sequence
ELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQE
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