ERCC4 Antibody - middle region : HRP (ARP58272_P050-HRP)

Product Specifications

Gene Name

Excision repair cross-complementing rodent repair deficiency, complementation group 4

Gene Aliases

XPF, RAD1, FANCQ, XFEPS, ERCC11

Gene ID

2072

Swiss Prot

Q92889

Accession Number

NP_005227

Host

Rabbit

Reactivity

Human, Rat, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ERCC4

Target

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause

Partner Proteins

Vpr; SLX4; UBC; MSH2; ERCC1; ALYREF; VPS26A; UBE2B; SLX1A; POLR2A; SUMO2; GTF2H1; SPTAN1; ERCC6; TADA2A; FANCG; PLK1; SLX4IP; SLX1B; RAD52; SPTA1; FANCA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

ERCC4 is supported by BioGPS gene expression data to be expressed in PANC1

Concentration

0.5 mg/ml

Homology

Dog: 83%; Horse: 85%; Human: 100%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.