ERCC4 Antibody - middle region : FITC (ARP58272_P050-FITC)
Selected Variant
ARP58272_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Excision repair cross-complementing rodent repair deficiency, complementation group 4
Gene Aliases
XPF, RAD1, FANCQ, XFEPS, ERCC11
Gene ID
2072
Swiss Prot
Q92889
Accession Number
NP_005227
Host
Rabbit
Reactivity
Human, Rat, Dog, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ERCC4
Target
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause
Partner Proteins
Vpr; SLX4; UBC; MSH2; ERCC1; ALYREF; VPS26A; UBE2B; SLX1A; POLR2A; SUMO2; GTF2H1; SPTAN1; ERCC6; TADA2A; FANCG; PLK1; SLX4IP; SLX1B; RAD52; SPTA1; FANCA
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
ERCC4 is supported by BioGPS gene expression data to be expressed in PANC1
Concentration
0.5 mg/ml
Homology
Dog: 83%; Horse: 85%; Human: 100%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
101kDa
Shipping Conditions
Wet Ice
Protein Length
916
NCBI Gene Symbol
ERCC4
NCBI GB Accession Number
ERCC4
Host or Source
Rabbit
Protein Name
DNA repair endonuclease XPF
Nucleotide Accession Number
NM_005236
Peptide Sequence
FLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERAST
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