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ACD Antibody - C-terminal region : Biotin (ARP58254_P050-Biotin)

Product Specifications

Gene Name

Adrenocortical dysplasia homolog (mouse)

Gene Aliases

PIP1, PTOP, TPP1, TINT1

Gene ID

65057

Swiss Prot

Q96AP0

Accession Number

NP_001075955

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ACD

Target

ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

Partner Proteins

TINF2; ANXA8L1; POT1; USP7; CUL5; ZNF790; PAGE2; APOBEC3F; NUDCD2; LRRC25; TRIM15; AFAP1L2; TBC1D10A; PDLIM2; RBKS; ANKMY2; PGM2; SBDS; LGALSL; DBNL; AIPL1; NCDN; STIP1; TOMM34; NUDC; TRIM16; TUBB4B; STUB1; FAM131B; BAG3; RECQL4; EIF3G; FKBP6; YWHAE; TUBB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Hockemeyer, D., (2007) Nat. Struct. Mol. Biol. 14 (8), 754-761

Shipping Conditions

Wet Ice

Protein Length

544

NCBI Gene Symbol

ACD

NCBI GB Accession Number

ACD

Host or Source

Rabbit

Protein Name

Adrenocortical dysplasia protein homolog

Nucleotide Accession Number

NM_001082486

Peptide Sequence

SSQPSPAICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQAL

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