SUMO3 Antibody - middle region : Biotin (ARP58247_P050-Biotin)

Product Specifications

Gene Name

SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)

Gene Aliases

SMT3A, Smt3B, SMT3H1, SUMO-3

Gene ID

6612

Swiss Prot

P55854

Accession Number

NP_008867

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SUMO3

Target

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability.SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

PML; USPL1; UBC; HIF1A; ESRRA; EP300; SENP1; USP25; SENP5; SENP2; TP53; SP100; RANGAP1; RGPD8; SUMO3; TRA2B; SDHA; GNB2; GNB1; GART; GAPDH; XRCC6; FLNA; FEN1; FASN; FBL; ENO1; EMD; EIF4A2; EIF4A1; EIF2S1; EEF2; EEF1G; EEF1D; EEF1A1; DNMT1; DYNC1H1; DHX15

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

SUMO3 is strongly supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.