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BPGM Antibody - middle region : HRP (ARP58217_P050-HRP)

Product Specifications

Gene Name

2,3-bisphosphoglycerate mutase

Gene Aliases

DPGM, ECYT8

Gene ID

669

Swiss Prot

P07738

Accession Number

NP_001715

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human BPGM

Target

BPGM belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily. It plays a major role in regulating hemoglobin oxygen affinity as a consequence of controlling 2,3-BPG concentration. It can also catalyze the reaction of EC 5.4.2.1 (mutase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.

Partner Proteins

UBC; EHD2; ATF6; NEK3; EGR2; CEL; ATP4B; SPEN; GRB2; AKT1; GAPDH

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 93%; Zebrafish: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Wang, Y., (2006) J. Biol. Chem. 281 (51), 39642-39648

Shipping Conditions

Wet Ice

Protein Length

259

NCBI Gene Symbol

BPGM

NCBI GB Accession Number

BPGM

Host or Source

Rabbit

Protein Name

Bisphosphoglycerate mutase

Nucleotide Accession Number

NM_001724

Peptide Sequence

EQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLK

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