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HOXA11 Antibody - middle region : HRP (ARP58161_P050-HRP)

Selected Variant

ARP58161_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Homeobox A11

Gene Aliases

HOX1, HOX1I, RUSAT1

Gene ID

3207

Swiss Prot

P31270

Accession Number

NP_005514

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HOXA11

Target

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

PGBD3; UBC; YY1; HDAC2; HDAC1; FOXO1; GMNN; MEIS1; CREBBP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 100%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Connell, K.A., (2008) J. Clin. Invest. 118 (3), 1050-1055

Shipping Conditions

Wet Ice

Protein Length

313

NCBI Gene Symbol

HOXA11

NCBI GB Accession Number

HOXA11

Host or Source

Rabbit

Protein Name

Homeobox protein Hox-A11

Nucleotide Accession Number

NM_005523

Peptide Sequence

FETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSD

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