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GTF2A1 Antibody - N-terminal region : Biotin (ARP58154_P050-Biotin)

Product Specifications

Gene Name

General transcription factor IIA, 1, 19/37kDa

Gene Aliases

TF2A1, TFIIA, TFIIAL, TFIIA-42

Gene ID

2957

Swiss Prot

P52655

Accession Number

NP_056943

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2A1

Target

GTF2A1 belongs to the TFIIA subunit 1 family. It is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. This protein induces a conformational change within the TBP/TATA complex that enhances its stability under both in vitro and physiological salt conditions.

Partner Proteins

HUWE1; NFYA; GTF2A2; UBC; FAM129B; SNX6; RPUSD2; GORASP2; BOP1; ATG7; PDIA6; UGDH; TBCD; SARS; RDX; ME1; GARS; BLMH; ATP6V1C1; LMNA; TAF4B; SIRT1; ZEB1; SUMO3; SUMO1; TBP; TERF2; MKX; KDM5B; CREB1; TBPL2; DOCK7; MYLK2; CNOT1; GCN1L1; TBPL1; TAF6; TAF5; TA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

References & Citations

Hieb, A.R., (2007) J. Mol. Biol. 372 (3), 619-632

Shipping Conditions

Wet Ice

Protein Length

376

NCBI Gene Symbol

GTF2A1

NCBI GB Accession Number

GTF2A1

Host or Source

Rabbit

Protein Name

Transcription initiation factor IIA subunit 1

Nucleotide Accession Number

NM_015859

Peptide Sequence

ANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLM

Subunit

1

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