ASH2L Antibody - N-terminal region : HRP (ARP58134_P050-HRP)
Product Specifications
Gene Name
Ash2 (absent, small, or homeotic) -like (Drosophila)
Gene Aliases
ASH2, Bre2, ASH2L1, ASH2L2
Gene ID
9070
Swiss Prot
Q9UBL3
Accession Number
NP_004665
Host
Rabbit
Reactivity
Human, Mouse, Dog, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ASH2L
Target
ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. It may function as a transcriptional regulator and play a role in hematopoiesis.
Partner Proteins
CXXC1; DPY30; SETD1A; RBBP5; PPARG; KMT2A; KMT2D; UBC; SENP3; KDM6A; PPP1CC; SMAD9; KDM6B; WWP1; BRCA1; BARD1; WDR5; MEN1; USF1; KMT2C; HCFC2; SETD1B; KDM4B; KMT2B; HCFC1; ESR1; CDC73; HIST3H3; PYGO2; WDR82; PSMC5; PRMT1; E2F4; E2F1; PAGR1; NCOA6; PAXIP1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 85%; Horse: 85%; Human: 100%; Mouse: 85%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
69kDa
References & Citations
Goei, V.L., (2008) Cancer Res. 68 (3), 749-758
Shipping Conditions
Wet Ice
Protein Length
628
NCBI Gene Symbol
ASH2L
NCBI GB Accession Number
ASH2L
Host or Source
Rabbit
Protein Name
Set1/Ash2 histone methyltransferase complex subunit ASH2
Nucleotide Accession Number
NM_004674
Peptide Sequence
AAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTL
Subunit
ASH2
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