TRIM25 Antibody - middle region : HRP (ARP58105_P050-HRP)
Selected Variant
ARP58105_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Tripartite motif containing 25
Gene Aliases
EFP, Z147, RNF147, ZNF147
Gene ID
7706
Swiss Prot
Q14258
Accession Number
NP_005073
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TRIM25
Target
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Partner Proteins
UBC; DDX58; SUMO2; AMFR; UBE2D1; SUMO1; PCNA; USP15; UBA1; RPS27A; RPA1; KIF5B; HSPA1L; HSPA1B; HSPA1A; EEF1A2; ACLY; SUZ12; RNF2; EZH2; BMI1; HECW2; TRIM25; TRIM8; TFG; GRIK2; ESR1; OTUB2; USP39; VCP; WARS; UAP1; UBXN6; UBE2S; UBE2D2; TRAF6; ISG15; UBE2D
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 79%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
71kDa
Shipping Conditions
Wet Ice
Protein Length
630
NCBI Gene Symbol
TRIM25
NCBI GB Accession Number
TRIM25
Host or Source
Rabbit
Protein Name
E3 ubiquitin/ISG15 ligase TRIM25
Nucleotide Accession Number
NM_005082
Peptide Sequence
LLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLT
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