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TBX6 Antibody - middle region : Biotin (ARP58088_P050-Biotin)

Product Specifications

Gene Name

T-box 6

Gene Aliases

SCDO5

Gene ID

6911

Swiss Prot

O95947

Accession Number

NP_004599

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TBX6

Target

TBX6 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures. Transcript variants encoding different isoforms have been noted for this gene.

Partner Proteins

HSFY1; C1orf94; RBPMS; TOX4; PSMA3; MEOX2; PRMT1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 92%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 100%; Rabbit: 92%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Ghebranious, N., (er) J. Bone Miner. Res. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

436

NCBI Gene Symbol

TBX6

NCBI GB Accession Number

TBX6

Host or Source

Rabbit

Protein Name

T-box transcription factor TBX6

Nucleotide Accession Number

NM_004608

Peptide Sequence

PSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAP

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