SIAH2 Antibody - N-terminal region : Biotin (ARP58071_P050-Biotin)

Product Specifications

Gene Name

Siah E3 ubiquitin protein ligase 2

Gene Aliases

HSiah2

Gene ID

6478

Swiss Prot

O43255

Accession Number

NP_005058

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SIAH2

Target

SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

EGLN3; XAF1; HIPK2; UBE2D1; UBE2L6; SIAH2; UBE2D3; UBC; PPP1R13B; TP53BP2; NFE2L2; USP19; AR; UBE2I; STAT3; MYD88; EEF1D; CCBE1; SETD2; HIPK3; TNK2; KAT5; KAT2B; UBE2D2; TPX2; PML; ATN1; PSMD4; PPP1R12A; EGLN2; SH3RF1; EGLN1; DYRK2; PPP1CC; AFF1; DCC; CEB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

SIAH2 is supported by BioGPS gene expression data to be expressed in HepG2, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 92%; Human: 100%; Mouse: 80%; Pig: 93%; Rat: 80%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.