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POLE3 Antibody - N-terminal region : Biotin (ARP58048_P050-Biotin)

Product Specifications

Gene Name

Polymerase (DNA directed), epsilon 3 (p17 subunit)

Gene Aliases

P17, YBL1, CHRAC2, CHRAC17, CHARAC17

Gene ID

54107

Swiss Prot

Q9NRF9

Accession Number

NP_059139

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POLE3

Target

POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM].

Partner Proteins

CHRAC1; DRAP1; DR1; UBC; NANS; ANXA6; gag-pol; POLE4; CPSF2; POLE; APP; YEATS2; POLE2; Cebpb; SUMO2; XRCC5; BAZ1A; SMARCA5; RAD17

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

147

NCBI Gene Symbol

POLE3

NCBI GB Accession Number

POLE3

Host or Source

Rabbit

Protein Name

DNA polymerase epsilon subunit 3

Nucleotide Accession Number

NM_017443

Peptide Sequence

AERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSC

Subunit

3

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