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NFE2 Antibody - middle region : Biotin (ARP58037_P050-Biotin)

Product Specifications

Gene Name

Nuclear factor (erythroid-derived 2), 45kDa

Gene Aliases

P45, NF-E2

Gene ID

4778

Swiss Prot

Q16621

Accession Number

NP_006154

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NFE2

Target

NFE2 is required for activity at the locus control region (LCR) upstream of the globin gene complexes.It requires p18 NF-E2 for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron.

Partner Proteins

BTRC; NFE2L3; NFE2L2; NFE2; ATF4; Dlg4; TXN; ITCH; Yap1; Nedd4; WWP1; MAPK8; KAT2B; SCAND1; SSX5; HMGN1; ELF5; PHYHIP; MAFF; MAFG; PEX14; MAFK; CREBBP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

References & Citations

McCormack, M.P., (2006) Blood 108 (7), 2248-2256

Shipping Conditions

Wet Ice

Protein Length

373

NCBI Gene Symbol

NFE2

NCBI GB Accession Number

NFE2

Host or Source

Rabbit

Protein Name

Transcription factor NF-E2 45 kDa subunit

Nucleotide Accession Number

NM_006163

Peptide Sequence

KPLSLSGLLSEPLQDPLALLDIGLPAGPPKPQEDPESDSGLSLNYSDAES

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