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MID1 Antibody - N-terminal region : Biotin (ARP58031_P050-Biotin)

Product Specifications

Gene Name

Midline 1 (Opitz/BBB syndrome)

Gene Aliases

OS, FXY, OSX, OGS1, XPRF, BBBG1, GBBB1, MIDIN, RNF59, ZNFXY, TRIM18

Gene ID

4281

Swiss Prot

O15344-2

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human MID1

Target

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse.

Partner Proteins

STK36; MID2; UBE2E3; DYRK4; UBE2E2; UBE2E1; UBE2D3; UBE2D2; UBE2D1; PKN1; PPP2R4; PPP2CA; MID1; MEOX1; FKBP1A; EHHADH; BYSL; TCEANC; UBTD1; OTUB2; GMCL1; HTT; IGBP1; PNKP; MID1IP1; GNB2L1; RPS8; RPS3; NPM1; HSP90AA1; EEF1A1; ANXA2; UBC; UBE2D4; UBE2N; ELA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-MID1 (ARP58031_P050-Biotin) antibody

Protein Length

552

NCBI Gene Symbol

MID1

NCBI GB Accession Number

MID1

Host or Source

Rabbit

Protein Name

Midline-1

Peptide Sequence

PTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAF

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