ATF5 Antibody - middle region: Biotin (ARP57977_P050-Biotin)
Product Specifications
Gene Name
Activating transcription factor 5
Gene Aliases
ATFX, HMFN0395
Gene ID
22809
Swiss Prot
B3KND3
Accession Number
NP_036200
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ATF5
Target
ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma.
Partner Proteins
CEBPE; CEBPA; GIT2; ATXN1; EP300; CCND3; GABBR2; DISC1; GABBR1; CEBPG; CDC34; TRIB3; UBC; CD34
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
31kDa
Shipping Conditions
Wet Ice
Protein Length
282
NCBI Gene Symbol
ATF5
Protein Name
Cyclic AMP-dependent transcription factor ATF-5
Nucleotide Accession Number
NM_012068
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