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IKZF2 Antibody - middle region : FITC (ARP57975_P050-FITC)

Product Specifications

Gene Name

IKAROS family zinc finger 2 (Helios)

Gene Aliases

ANF1A2, HELIOS, ZNF1A2, ZNFN1A2

Gene ID

22807

Swiss Prot

Q9UKS7

Accession Number

NP_057344

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IKZF2

Target

IKZF2 is associates with Ikaros at centromeric heterochromatin.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Partner Proteins

LONRF1; CTBP2; AQP1; CTBP1; UBC; HDAC1; HOXA1; NOTCH1; IKZF4; IKZF5; IKZF2; IKZF1; IKZF3; SIN3A; SIN3B; HDAC5; HDAC2; CHD4; HDAC4

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Antica, M., (2008) Blood 111 (6), 3296-3297

Shipping Conditions

Wet Ice

Protein Length

526

NCBI Gene Symbol

IKZF2

NCBI GB Accession Number

IKZF2

Host or Source

Rabbit

Protein Name

Zinc finger protein Helios

Nucleotide Accession Number

NM_016260

Peptide Sequence

EREASPSNSCLDSTDSESSHDDHQSYQGHPALNPKRKQSPAYMKEDVKAL

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