Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ERCC8 Antibody - N-terminal region : HRP (ARP57955_P050-HRP)

Product Specifications

Gene Name

Excision repair cross-complementing rodent repair deficiency, complementation group 8

Gene Aliases

CSA, CKN1, UVSS2

Gene ID

1161

Swiss Prot

B2RB64

Accession Number

NP_000073

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC8

Target

ERCC8 is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS) .This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS) . CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Partner Proteins

CUL4A; CUL4B; DDB1; RUVBL2; ZNF24; PCNA; H1F0; ERCC6; UVSSA; DDA1; RFWD2; COPS4; COPS6; COPS3; TOP1; TP53; SSBP1; OGG1; MDM2; GTF2H2; CUL5; GPS1; DDB2; COPS2; COPS7A; COPS5; COPS8; RBX1; POLR2A; HMGN1; EP300; UBC; CSNK2B; XAB2; UQCRQ; CBR1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Bethke, L., (2008) J. Natl. Cancer Inst. 100 (4), 270-276

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ERCC8 (ARP57955_P050-HRP) antibody

Protein Length

396

NCBI Gene Symbol

ERCC8

NCBI GB Accession Number

ERCC8

Host or Source

Rabbit

Protein Name

DNA excision repair protein ERCC-8

Nucleotide Accession Number

NM_000082

Peptide Sequence

DLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFD

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FITC anti-mouse CD28
GT02925 500 µg

FITC anti-mouse CD28

Ask
View Details
Slc25a43 (NM_001085497) Mouse Untagged Clone
MC212464 10 µg

Slc25a43 (NM_001085497) Mouse Untagged Clone

Ask
View Details
Rabbit Polyclonal MCAF1 Antibody [DyLight 680]
NB100-438FR 0.1 mL

Rabbit Polyclonal MCAF1 Antibody [DyLight 680]

Ask
View Details
Factor V (6A5) HRP
sc-13512 HRP 200 µg/mL

Factor V (6A5) HRP

Ask
View Details