TCF7L1 Antibody - N-terminal region : Biotin (ARP57917_P050-Biotin)
Product Specifications
Gene Name
Transcription factor 7-like 1 (T-cell specific, HMG-box)
Gene Aliases
TCF3, TCF-3
Gene ID
83439
Swiss Prot
Q9HCS4
Accession Number
NP_112573
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1
Target
TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Partner Proteins
UBC; mdfic; Mdfi; DAZAP2; CTNNB1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
63kDa
References & Citations
Hillier, L.W., (2005) Nature 434 (7034), 724-731
Shipping Conditions
Wet Ice
Protein Length
588
NCBI Gene Symbol
TCF7L1
NCBI GB Accession Number
TCF7L1
Host or Source
Rabbit
Protein Name
Transcription factor 7-like 1
Nucleotide Accession Number
NM_031283
Peptide Sequence
ESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYPG
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