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PCSK6 Antibody - N-terminal region : FITC (ARP57880_P050-FITC)

Product Specifications

Gene Name

Proprotein convertase subtilisin/kexin type 6

Gene Aliases

SPC4, PACE4

Gene ID

5046

Swiss Prot

Q63415

Accession Number

NP_612193

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PCSK6

Target

PCSK6 is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. This gene is thought to play a role in tumor progression.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

Env; UBC; CACNA1A; RCN3; FLG; PMCH; PCSK6

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

References & Citations

Yuasa, K., Gene 402 (1-2), 103-110 (2007)

Shipping Conditions

Wet Ice

Protein Length

975

NCBI Gene Symbol

PCSK6

NCBI GB Accession Number

PCSK6

Host or Source

Rabbit

Protein Name

Proprotein convertase subtilisin/kexin type 6

Nucleotide Accession Number

NM_138320

Peptide Sequence

NYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGI

Frequently Asked Questions

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