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PPHLN1 Antibody - N-terminal region : FITC (ARP57819_P050-FITC)

Selected Variant

ARP57819_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Periphilin 1

Gene Aliases

CR, HSPC206, HSPC232

Gene ID

51535

Swiss Prot

Q8NEY8-2

Accession Number

NP_958923

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PPHLN1

Target

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Partner Proteins

MTUS2; SNCAIP; CCDC57; TSGA10; UBC; BMI1; CLK2; CDK6; PAXIP1; BRCA1; APP; VIM; ELAVL1; NAGK; SEPT8; CDC37; SQSTM1; UFD1L; TP53BP2; BCL2L1; PPHLN1; PPL; CASP5; TOMM20; TGM2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 92%; Horse: 80%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 85%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

Shipping Conditions

Wet Ice

Protein Length

374

NCBI Gene Symbol

PPHLN1

NCBI GB Accession Number

PPHLN1

Host or Source

Rabbit

Protein Name

Periphilin-1

Nucleotide Accession Number

NM_201515

Peptide Sequence

MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDR

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