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TH1L Antibody - N-terminal region : Biotin (ARP57805_P050-Biotin)

Product Specifications

Gene Name

TH1-like (Drosophila)

Gene Aliases

TH1, TH1L, NELF-C, NELF-D, HSPC130

Gene ID

51497

Swiss Prot

Q8IXH7

Accession Number

NP_945327

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TH1L

Target

The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.

Partner Proteins

UBC; NELFA; PRMT5; ZNF638; UBE3A; POLR2C; SMAD4; ARAF; NELFB; NELFE; SUMO2; ATP1A1; CACNA1A; AR; FRMD5; ARPC4; HDAC11; ENDOV; SERF2; MTA1; AAMP; DNAJA1; TXK; GSTM4; EPRS; COPB2; RPS26; RPS14; RPS11; COX2; MCM7; EIF4G1; COX6C; COX6B1; COX5B; COX4I1; COX5A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

NELFCD is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

66kDa

Shipping Conditions

Wet Ice

Protein Length

590

NCBI Gene Symbol

NELFCD

NCBI GB Accession Number

NELFCD

Host or Source

Rabbit

Protein Name

Negative elongation factor C/D

Nucleotide Accession Number

NM_198976

Peptide Sequence

GEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLS

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