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PPP2R1A Antibody - N-terminal region : Biotin (ARP57780_P050-Biotin)

Selected Variant

ARP57780_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Protein phosphatase 2, regulatory subunit A, beta

Gene Aliases

MRD36, PP2AA, PR65A, PP2AAALPHA, PP2A-Aalpha

Gene ID

5518

Swiss Prot

A8K7B7

Accession Number

NP_055040

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of HUMAN PPP2R1A

Target

PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A is an alpha isoform of the constant regulatory subunit A.

Partner Proteins

CSDC2; UBC; PPP2R2A; PPP2R1B; PPP2CB; POLDIP2; MOB4; SRGAP2; ANKLE2; PSIP1; ESPL1; PPFIA3; PPFIA1; IRS4; CCDC6; TFAM; PPP1R12B; HSPA7; HSPA1A; FECH; CTNNA2; CLCN6; STRN; RPS19; RPS3; PPP2R5E; PPP2R5D; PPP2R5C; PPP2CA; PEX1; LOC730668; DGKH; RAVER1; CCDC43

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

Shipping Conditions

Wet Ice

Protein Length

589

NCBI Gene Symbol

PPP2R1A

NCBI GB Accession Number

PPP2R1A

Host or Source

Rabbit

Protein Name

Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform EMBL EAW72066.1

Nucleotide Accession Number

NM_014225

Peptide Sequence

IDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVL

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