PYCR1 Antibody - middle region : Biotin (ARP57751_P050-Biotin)

Product Specifications

Gene Name

Pyrroline-5-carboxylate reductase 1

Gene Aliases

P5C, P5CR, PRO3, PYCR, PIG45, PP222, ARCL2B, ARCL3B

Gene ID

5831

Swiss Prot

A6NFM2

Accession Number

NP_722546

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PYCR1

Target

This gene encodes an enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. The protein forms a homopolymer and localizes

Partner Proteins

FUS; SUMO2; NEDD8; MDM2; SUZ12; RNF2; BMI1; HNRNPD; BAG3; BNIPL; UBC; ITGA4; DAB2; MDC1; CUL3; NUDT21; CDK2AP2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

PYCR1 is supported by BioGPS gene expression data to be expressed in 721_B, HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

References & Citations

Meng, Z., (2006) J. Mol. Biol. 359 (5), 1364-1377

Shipping Conditions

Wet Ice

Protein Length

316

NCBI Gene Symbol

PYCR1

NCBI GB Accession Number

PYCR1

Host or Source

Rabbit

Protein Name

Pyrroline-5-carboxylate reductase 1, mitochondrial

Nucleotide Accession Number

NM_153824

Peptide Sequence

RSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELGSPE

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