PYCR1 Antibody - middle region : Biotin (ARP57750_P050-Biotin)

Product Specifications

Gene Name

Pyrroline-5-carboxylate reductase 1

Gene Aliases

P5C, P5CR, PRO3, PYCR, PIG45, PP222, ARCL2B, ARCL3B

Gene ID

5831

Swiss Prot

A6NFM2

Accession Number

NP_722546

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PYCR1

Target

This gene encodes an enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. The protein forms a homopolymer and localizes

Partner Proteins

FUS; SUMO2; NEDD8; MDM2; SUZ12; RNF2; BMI1; HNRNPD; BAG3; BNIPL; UBC; ITGA4; DAB2; MDC1; CUL3; NUDT21; CDK2AP2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

PYCR1 is supported by BioGPS gene expression data to be expressed in HEK293T, HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

References & Citations

Meng, Z., (2006) J. Mol. Biol. 359 (5), 1364-1377

Shipping Conditions

Wet Ice

Protein Length

316

NCBI Gene Symbol

PYCR1

NCBI GB Accession Number

PYCR1

Host or Source

Rabbit

Protein Name

Pyrroline-5-carboxylate reductase 1, mitochondrial

Nucleotide Accession Number

NM_153824

Peptide Sequence

KMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIR

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