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RAD51L1 Antibody - middle region : HRP (ARP57721_P050-HRP)

Selected Variant

ARP57721_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

RAD51 homolog B (S. cerevisiae)

Gene Aliases

REC2, R51H2, RAD51L1

Gene ID

5890

Swiss Prot

O15315-1

Accession Number

NP_598194

Host

Rabbit

Reactivity

Human, Mouse, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RAD51L1

Target

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Partner Proteins

FAM9B; SWSAP1; UBC; HIST1H2BG; HIST2H4A; RAD51D; HIST1H3A; RAD51C; H1F0; XRCC2; RAD51; HIST1H1A; HIST3H2BB; HIST3H3; HIST4H4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RAD51B is supported by BioGPS gene expression data to be expressed in COLO205

Concentration

0.5 mg/ml

Homology

Cow: 100%; Human: 100%; Mouse: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

Shipping Conditions

Wet Ice

Protein Length

350

NCBI Gene Symbol

RAD51B

NCBI GB Accession Number

RAD51B

Host or Source

Rabbit

Protein Name

DNA repair protein RAD51 homolog 2

Nucleotide Accession Number

NM_133510

Peptide Sequence

IPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVIAALGNTW

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