OPA1 Antibody - N-terminal region: FITC (ARP57715_P050-FITC)
Product Specifications
Gene Name
Optic atrophy 1 (autosomal dominant)
Gene Aliases
NPG, NTG, MGM1, BERHS, largeG, MTDPS14
Gene ID
4976
Swiss Prot
E5KLK2
Accession Number
NP_570844
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC; PARK2; MYC; HSP90AA5P; NIT2; HTRA2; NPTX1; NDUFS8; NDUFS1; NDUFA9; ILF3; HADHB; ECH1; DNASE2; APP; SMAD3; SMAD2; CAND1; CUL3; ELAVL1; MME
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
102kDa
Shipping Conditions
Wet Ice
Protein Length
924
NCBI Gene Symbol
OPA1
Protein Name
Mitochondrial dynamin-like 120 kDa protein EMBL ADP90061.1
Nucleotide Accession Number
NM_130831
Curated Selection
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