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MYL6 Antibody - middle region : Biotin (ARP57712_P050-Biotin)

Product Specifications

Gene Name

Myosin, light chain 6, alkali, smooth muscle and non-muscle

Gene Aliases

LC17, ESMLC, LC17A, LC17B, MLC-3, MLC1SM, MLC3NM, MLC3SM, LC17-GI, LC17-NM

Gene ID

4637

Swiss Prot

P60660

Accession Number

NP_524147

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MYL6

Target

MYL6 contains 3 EF-hand domains. It is the regulatory light chain of myosin. MYL6 does not bind calcium. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.

Partner Proteins

ADAMTS12; UBC; MDM2; SUZ12; MYL12A; MYH9; MYH14; GRIPAP1; UBD; GLP1R; PAN2; VCAM1; MLH1; ITGA4; FN1; TSGA10; ESR1; HSP90AB1; DES; ATP5B; MYL6B; LRRK2; CUL1; CDK2; ARRB1; ARRB2; SUMO2; SRRM2; USP45; USP46; USP18; MOB4; DNAJB9; NUDT21; EWSR1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

MYL6 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Fu, Z.Y., (2006) Acta Biochim. Biophys. Sin. (Shanghai) 38 (9), 625-632

Shipping Conditions

Wet Ice

Protein Length

151

NCBI Gene Symbol

MYL6

NCBI GB Accession Number

MYL6

Host or Source

Rabbit

Protein Name

Myosin light polypeptide 6

Nucleotide Accession Number

NM_079423

Peptide Sequence

PMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMT

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