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MYL6 Antibody - N-terminal region : FITC (ARP57711_P050-FITC)

Product Specifications

Gene Name

Myosin, light chain 6, alkali, smooth muscle and non-muscle

Gene Aliases

LC17, ESMLC, LC17A, LC17B, MLC-3, MLC1SM, MLC3NM, MLC3SM, LC17-GI, LC17-NM

Gene ID

4637

Swiss Prot

P60660

Accession Number

NP_524147

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MYL6

Target

MYL6 contains 3 EF-hand domains. It is the regulatory light chain of myosin. MYL6 does not bind calcium. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.

Partner Proteins

ADAMTS12; UBC; MDM2; SUZ12; MYL12A; MYH9; MYH14; GRIPAP1; UBD; GLP1R; PAN2; VCAM1; MLH1; ITGA4; FN1; TSGA10; ESR1; HSP90AB1; DES; ATP5B; MYL6B; LRRK2; CUL1; CDK2; ARRB1; ARRB2; SUMO2; SRRM2; USP45; USP46; USP18; MOB4; DNAJB9; NUDT21; EWSR1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

MYL6 is supported by BioGPS gene expression data to be expressed in 721_B, HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 90%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Fu, Z.Y., (2006) Acta Biochim. Biophys. Sin. (Shanghai) 38 (9), 625-632

Shipping Conditions

Wet Ice

Product Datasheet

Anti-MYL6 (ARP57711_P050-FITC) antibody

Protein Length

151

NCBI Gene Symbol

MYL6

NCBI GB Accession Number

MYL6

Host or Source

Rabbit

Protein Name

Myosin light polypeptide 6

Nucleotide Accession Number

NM_079423

Peptide Sequence

CDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKV

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