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NECAB3 Antibody - N-terminal region : FITC (ARP57669_P050-FITC)

Product Specifications

Gene Name

N-terminal EF-hand calcium binding protein 3

Gene Aliases

NIP1, XB51, STIP3, EFCBP3, SYTIP2, APBA2BP, dJ63M2.4, dJ63M2.5

Gene ID

63941

Swiss Prot

Q96P71

Accession Number

NP_112509

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NECAB3

Target

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; APP; MYC; IKBKG; APBA2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 90%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 90%; Rat: 90%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-NECAB3 (ARP57669_P050-FITC) antibody

Protein Length

396

NCBI Gene Symbol

NECAB3

NCBI GB Accession Number

NECAB3

Host or Source

Rabbit

Protein Name

N-terminal EF-hand calcium-binding protein 3

Nucleotide Accession Number

NM_031232

Peptide Sequence

MACAGLLTVCLLRPPAPQPQPQTPRHPQLAPDPGPAGHTLFQDVFRRADK

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