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NECAB3 Antibody - N-terminal region : FITC (ARP57669_P050-FITC)

Selected Variant

ARP57669_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

N-terminal EF-hand calcium binding protein 3

Gene Aliases

NIP1, XB51, STIP3, EFCBP3, SYTIP2, APBA2BP, dJ63M2.4, dJ63M2.5

Gene ID

63941

Swiss Prot

Q96P71

Accession Number

NP_112509

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NECAB3

Target

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; APP; MYC; IKBKG; APBA2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 90%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 90%; Rat: 90%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

Shipping Conditions

Wet Ice

Protein Length

396

NCBI Gene Symbol

NECAB3

NCBI GB Accession Number

NECAB3

Host or Source

Rabbit

Protein Name

N-terminal EF-hand calcium-binding protein 3

Nucleotide Accession Number

NM_031232

Peptide Sequence

MACAGLLTVCLLRPPAPQPQPQTPRHPQLAPDPGPAGHTLFQDVFRRADK

Price

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