GREM2 Antibody - N-terminal region: HRP (ARP57635_P050-HRP)
Product Specifications
Gene Name
Gremlin 2
Gene Aliases
PRDC, DAND3, STHAG9, CKTSF1B2
Gene ID
64388
Swiss Prot
Q9H772
Accession Number
NP_071914
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GREM2
Target
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
Partner Proteins
BMP4; BMP2
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 93%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
17kDa
Shipping Conditions
Wet Ice
Protein Length
168
NCBI Gene Symbol
GREM2
Protein Name
Gremlin-2
Nucleotide Accession Number
NM_022469
Curated Selection
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