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MMP26 Antibody - C-terminal region : HRP (ARP57558_P050-HRP)

Selected Variant

ARP57558_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Matrix metallopeptidase 26

Gene Aliases

MGC126590, MGC126592

Gene ID

56547

Swiss Prot

Q9NRE1

Accession Number

NP_068573

Host

Rabbit

Reactivity

Human, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MMP26

Target

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.

Partner Proteins

SERPINA1; IGFBP1; MMP9

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MMP26 is supported by BioGPS gene expression data to be expressed in A549

Concentration

0.5 mg/ml

Homology

Human: 100%; Rat: 83%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

19kDa

Shipping Conditions

Wet Ice

Protein Length

261

NCBI Gene Symbol

MMP26

NCBI GB Accession Number

MMP26

Host or Source

Rabbit

Protein Name

Matrix metalloproteinase-26

Nucleotide Accession Number

NM_021801

Peptide Sequence

NLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQH

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