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EIF5A2 Antibody - N-terminal region : Biotin (ARP57402_P050-Biotin)

Selected Variant

ARP57402_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Eukaryotic translation initiation factor 5A2

Gene Aliases

EIF-5A2, eIF5AII

Gene ID

56648

Swiss Prot

Q9GZV4

Accession Number

NP_065123

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF5A2

Target

EIF5A2 is a mRNA-binding protein involved in translation elongation. EIF5A2 has an important function at the level of mRNA turnover, probably acting downstream of decapping.EIF5A2 is involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. EIF5A2 functions as a regulator of apoptosis.EIF5A2 mediates effects of polyamines on neuronal process extension and survival.EIF5A2 may play an important role in brain development and function, and in skeletal muscle stem cell differentiation.

Partner Proteins

NIF3L1; CDC23; SDCBP; REL; DHPS; FAM96B; UBC; MDM2; PTBP2; RAB30; CUL3; CUL4B; CDK2; VHL; OPTN; DCC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

Shipping Conditions

Wet Ice

Protein Length

153

NCBI Gene Symbol

EIF5A2

NCBI GB Accession Number

EIF5A2

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 5A-2

Nucleotide Accession Number

NM_020390

Peptide Sequence

MADEIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGK

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