H2AFY2 Antibody - middle region : FITC (ARP57281_P050-FITC)
Selected Variant
ARP57281_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
H2A histone family, member Y2
Gene Aliases
H2AFY2
Gene ID
55506
Swiss Prot
Q9P0M6
Accession Number
NP_061119
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human H2AFY2
Target
H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
Partner Proteins
UBC; SUZ12; EED; WWP1; CBX5; DIDO1; SUMO1; HDGF; tat
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
Shipping Conditions
Wet Ice
Protein Length
372
NCBI Gene Symbol
H2AFY2
NCBI GB Accession Number
H2AFY2
Host or Source
Rabbit
Protein Name
Core histone macro-H2A.2
Nucleotide Accession Number
NM_018649
Peptide Sequence
PRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRT
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