PIDD1 Antibody - middle region : Biotin (ARP57270_P050-Biotin)

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6) -associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

CRADD; CRYAB; MDFI; SOX8; KEAP1; TEAD3; MAFG; AFP; RPAP3; FANCI; SENP3; TRIM32; ANP32B; HAX1; TELO2; NUP93; AIFM1; RFC5; RFC4; PRKDC; PPP6C; POLR2B; POLD1; PCNA; PRDX1; MCM7; ERCC5; ERCC2; DDB1; CASP2; FADD; RIPK1; IKBKG; CCDC85B; EFEMP2; MADD

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.