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CENPN Antibody - middle region: Biotin (ARP57258_P050-Biotin)

Product Specifications

Gene Name

Centromere protein N

Gene Aliases

BM039, CENP-N, ICEN32, C16orf60

Gene ID

55839

Accession Number

NP_001094095

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CENPN

Target

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128) . CENPN is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]) .

Partner Proteins

UBC; CENPP; CENPL; CENPU; CENPO; CENPM; CENPH; CENPK; CENPN; CENPQ; CENPI; CENPA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IF, WB

Purification

Affinity Purified

Sample Type

CENPN is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/mL

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

Shipping Conditions

Wet Ice

Protein Length

353

NCBI Gene Symbol

CENPN

Nucleotide Accession Number

NM_001100625

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