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ARFGAP1 Antibody - middle region : FITC (ARP57149_P050-FITC)

Selected Variant

ARP57149_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

ADP-ribosylation factor GTPase activating protein 1

Gene Aliases

ARF1GAP, HRIHFB2281

Gene ID

55738

Swiss Prot

Q8N6T3

Accession Number

NP_060679

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ARFGAP1

Target

The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1) . The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

KRTAP10-9; KRTAP9-2; KRTAP3-2; GABARAPL2; GRN; FOS; TRIM23; UBC; RPL22; HK1; RAD52; RPL11; RFC3; PRKACB; APOE; APOC3; APOB; ASB10; RASIP1; RAB23; COPS5; MED27; REEP5; APP; LRRK2; MAP1LC3B; TK1; SMN1; TMED2; CYTH2; COPA; CSNK1D; RGS2; KDELR1; ARF1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

Shipping Conditions

Wet Ice

Protein Length

406

NCBI Gene Symbol

ARFGAP1

NCBI GB Accession Number

ARFGAP1

Host or Source

Rabbit

Protein Name

ADP-ribosylation factor GTPase-activating protein 1

Nucleotide Accession Number

NM_018209

Peptide Sequence

GQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFL

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