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TESC Antibody - C-terminal region : Biotin (ARP57060_P050-Biotin)

Product Specifications

Gene Name

Tescalcin

Gene Aliases

TSC, CHP3

Gene ID

54997

Swiss Prot

Q96BS2

Accession Number

NP_060369

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human TESC

Target

TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane and promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner and inhibits the phosphatase activity of calcineurin.

Partner Proteins

WBP11; UBC; CCDC91; HMG20A; TESC; RAI1; DYNLT3; SLC9A1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TESC is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-TESC (ARP57060_P050-Biotin) antibody

Protein Length

214

NCBI Gene Symbol

TESC

NCBI GB Accession Number

TESC

Host or Source

Rabbit

Protein Name

Calcineurin B homologous protein 3

Nucleotide Accession Number

NM_017899

Peptide Sequence

DSDGRITLEEYRNVVEELLSGNPHIEKESARSIADGAMMEAASVCMGQME

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