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PNRC2 Antibody - middle region : Biotin (ARP57028_P050-Biotin)

Selected Variant

ARP57028_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Proline-rich nuclear receptor coactivator 2

Gene Aliases

FLJ20312, MGC99541

Gene ID

55629

Swiss Prot

Q9NPJ4

Accession Number

NP_060231

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PNRC2

Target

PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.

Partner Proteins

DCP1A; ESRRG; UBC; SF1; GLOD4; SPAG9; ZBTB48; XRCC6; RORA; RARG; HNF4G; HNF4A; NR5A2; ESR2; ESR1; ZBTB16; RORB; ESRRA; RARA; AR; NR5A1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

Shipping Conditions

Wet Ice

Protein Length

139

NCBI Gene Symbol

PNRC2

NCBI GB Accession Number

PNRC2

Host or Source

Rabbit

Protein Name

Proline-rich nuclear receptor coactivator 2

Nucleotide Accession Number

NM_017761

Peptide Sequence

NQSWNSSLSGPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWVPVSFN

Price

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