OTUB1 Antibody - middle region : Biotin (ARP57000_P050-Biotin)
Product Specifications
Gene Name
OTU domain, ubiquitin aldehyde binding 1
Gene Aliases
OTB1, OTU1, HSPC263
Gene ID
55611
Swiss Prot
Q96FW1
Accession Number
NP_060140
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human OTUB1
Target
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitin
Partner Proteins
UBE2D4; ERN1; UBE2D3; UBC; SUMO2; TRAF3; NEDD8; SUMO1; NMRAL1; TP53; UBE2D1; RNF2; KDM1A; UBE2N; SMAD4; SMAD3; SMAD2; TNFSF12; BIRC3; BIRC2; SMAD9; ESR1; ACTB; UBE2D2; RNF126; ECT2; OTUD6B; DSTN; RFFL; TRIM63; TRIM55; PJA1; USP28; TRIM54; USP21; USP15; UB
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
OTUB1 is strongly supported by BioGPS gene expression data to be expressed in HEK293T, HepG2
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
31kDa
References & Citations
Juris, S.J., (2006) FEBS Lett. 580 (1), 179-183
Shipping Conditions
Wet Ice
Protein Length
271
NCBI Gene Symbol
OTUB1
NCBI GB Accession Number
OTUB1
Host or Source
Rabbit
Protein Name
Ubiquitin thioesterase OTUB1
Nucleotide Accession Number
NM_017670
Peptide Sequence
KIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAK
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