ERCC6L Antibody - N-terminal region : Biotin (ARP56997_P050-Biotin)

Product Specifications

Gene Name

Excision repair cross-complementing rodent repair deficiency, complementation group 6-like

Gene Aliases

PICH, RAD26L

Gene ID

54821

Swiss Prot

Q2NKX8

Accession Number

NP_060139

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC6L

Target

ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint.ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Partner Proteins

LMO4; UBC; HTT; BARD1; ACACA; Ercc6l; Plk1; RB1CC1; RPA3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 93%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

141kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ERCC6L (ARP56997_P050-Biotin) antibody

Protein Length

1250

NCBI Gene Symbol

ERCC6L

NCBI GB Accession Number

ERCC6L

Host or Source

Rabbit

Protein Name

DNA excision repair protein ERCC-6-like

Nucleotide Accession Number

NM_017669

Peptide Sequence

GDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQGDDEFTDVCNS

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