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SHC3 Antibody - middle region : Biotin (ARP56958_P050-Biotin)

Product Specifications

Gene Name

SHC (Src homology 2 domain containing) transforming protein 3

Gene Aliases

RAI, NSHC, SHCC, N-Shc

Gene ID

53358

Swiss Prot

Q92529

Accession Number

NP_058544

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SHC3

Target

SHC3 is a signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. SHC3 is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

Partner Proteins

KRT40; KRT31; GOLGA2; ERBB3; ERBB2; EGFR; SH3GL3; ARHGAP32; NTRK2; NTRK1; RET; FLT4; AXL; GRB2; ALK; APP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

References & Citations

Villanacci, V., (2008) Neurogastroenterol. Motil. 20 (3), 206-212

Shipping Conditions

Wet Ice

Protein Length

594

NCBI Gene Symbol

SHC3

NCBI GB Accession Number

SHC3

Host or Source

Rabbit

Protein Name

SHC-transforming protein 3

Nucleotide Accession Number

NM_016848

Peptide Sequence

RLKPRPHAPDTAQFAGKEQTYYQGRHLGDTFGEDWQQTPLRQGSSDIYST

Frequently Asked Questions

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