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POMP Antibody - C-terminal region: HRP (ARP56777_P050-HRP)

Product Specifications

Gene Name

Proteasome maturation protein

Gene Aliases

UMP1, PRAAS2, HSPC014, C13orf12, PNAS-110

Gene ID

51371

Swiss Prot

Q9Y244

Accession Number

NP_057016

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human POMP

Target

The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.

Partner Proteins

SHFM1; PSMA5; PSMA4; PSMA3; PSMA2; PSMG1; PSMB7; PSMB4; PSMB3; PSMB2; PSMA7; UBC; ECT2; DSTN; CPLX1; CD2BP2; UBE2V1; UBE2A; IGBP1; KCNA10; PSMB1; PSMA6; PSMA1; CANX; PSMG2; POMP; CUL1; PSMB10; PSMB9; PSMB8; PSMB6; PSMB5; GRB2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

Shipping Conditions

Wet Ice

Protein Length

141

NCBI Gene Symbol

POMP

Protein Name

Proteasome maturation protein

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