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PPP2R1A Antibody - N-terminal region : Biotin (ARP56741_P050-Biotin)

Product Specifications

Gene Name

Protein phosphatase 2, regulatory subunit A, alpha

Gene Aliases

MRD36, PP2AA, PR65A, PP2AAALPHA, PP2A-Aalpha

Gene ID

5518

Swiss Prot

P30153

Accession Number

NP_055040

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R1A

Target

PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A is an alpha isoform of the constant regulatory subunit A.This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

CSDC2; UBC; PPP2R2A; PPP2R1B; PPP2CB; POLDIP2; MOB4; SRGAP2; ANKLE2; PSIP1; ESPL1; PPFIA3; PPFIA1; IRS4; CCDC6; TFAM; PPP1R12B; HSPA7; HSPA1A; FECH; CTNNA2; CLCN6; STRN; RPS19; RPS3; PPP2R5E; PPP2R5D; PPP2R5C; PPP2CA; PEX1; LOC730668; DGKH; RAVER1; CCDC43

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65kDa

References & Citations

Hong, S., (2007) J. Biol. Chem. 282 (16), 12119-12126

Shipping Conditions

Wet Ice

Protein Length

589

NCBI Gene Symbol

PPP2R1A

NCBI GB Accession Number

PPP2R1A

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

Nucleotide Accession Number

NM_014225

Peptide Sequence

KAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYP

Subunit

A alpha isoform

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