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NIT1 Antibody - N-terminal region : Biotin (ARP56647_P050-Biotin)

Product Specifications

Gene Name

Nitrilase 1

Gene Aliases

MGC57670

Gene ID

4817

Swiss Prot

Q86X76

Accession Number

NP_005591

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NIT1

Target

NIT1 play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. NIT1 has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tum

Partner Proteins

ZFYVE9; ATXN1L; UBC; XRCC6

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

NIT1 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Pig: 93%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Semba, S., (2006) J. Biol. Chem. 281 (38), 28244-28253

Shipping Conditions

Wet Ice

Protein Length

327

NCBI Gene Symbol

NIT1

NCBI GB Accession Number

NIT1

Host or Source

Rabbit

Protein Name

Nitrilase homolog 1

Nucleotide Accession Number

NM_005600

Peptide Sequence

VREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYTQLAREC

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