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QARS Antibody - N-terminal region : Biotin (ARP56628_P050-Biotin)

Selected Variant

ARP56628_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Glutaminyl-tRNA synthetase

Gene Aliases

QARS, GLNRS, MSCCA, PRO2195

Gene ID

5859

Swiss Prot

P47897

Accession Number

NP_005042

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human QARS

Target

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA (Gln) is formed by transamidation of the misacylated Glu-tRNA (Gln) . Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.

Partner Proteins

TCF12; AES; KLC3; DTX2; LZTS2; VPS37B; HUWE1; TRAF4; TRIP13; SUMO2; STAU1; UBC; SUMO1; NEDD8; RNF2; EIF2B3; IQGAP1; AIMP2; VARS; TUBB2A; RPLP0; RPL27A; RPL27; RPL23A; RPL19; RPL15; RPL13; RPL10; RPL7A; RFC4; RARS; PTBP1; PSMC6; NMT1; MRE11A; MARS; IARS; D

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

Shipping Conditions

Wet Ice

Protein Length

775

NCBI Gene Symbol

QARS

NCBI GB Accession Number

QARS

Host or Source

Rabbit

Protein Name

Glutamine--tRNA ligase

Nucleotide Accession Number

NM_005051

Peptide Sequence

DQTLSLMEQLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQV

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