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NDUFS3 Antibody - middle region : Biotin (ARP56579_P050-Biotin)

Product Specifications

Gene Name

NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

Gene Aliases

CI-30, MC1DN8

Gene ID

4722

Swiss Prot

O75489

Accession Number

NP_004542

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NDUFS3

Target

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I) . Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.

Partner Proteins

HUWE1; UBC; PARK2; ADRB2; ILK; RASL10B; VCAM1; ITGA4; FN1; Htt; NDUFS7; TMEM14C; SAMM50; MRPL3; SURF1; SSBP1; SLC3A2; SDHA; NDUFV2; NDUFS8; NDUFV1; NDUFS2; NDUFA5; PARK7; CUL3; NDUFB6; NDUFA9; ND6; GZMA; MYC; ICT1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Vogel, R.O., (2007) J. Biol. Chem. 282 (10), 7582-7590

Shipping Conditions

Wet Ice

Protein Length

264

NCBI Gene Symbol

NDUFS3

NCBI GB Accession Number

NDUFS3

Host or Source

Rabbit

Protein Name

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

Nucleotide Accession Number

NM_004551

Peptide Sequence

EVKRVVAEPVELAQEFRKFDLNSPWEAFPVYRQPPESLKLEAGDKKPDAK

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